Selected references#

  • Hsueh-Chi Sherry Yen, Stephen J. Elledge. Identification of SCF Ubiquitin Ligase Substrates by Global Protein Stability Profiling. Science (2008)

  • Itay Koren et al. The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons. Cell (2018)

  • Richard T. Timms et al. A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation. Science (2019)

  • Richard T. Timms et al. Defining E3 ligase–substrate relationships through multiplex CRISPR screening. Nature Cell Biology (2023)

  • Zhang et al. Degrons: defining the rules of protein degradation. Nature Reviews Molecular Cell Biology (2025)